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Takeya Tsutsumi

Departments/Divisions
Department of Infectious Diseases, Infection Control and Prevention Service, Infection Control Center
Titles
M.D. , Ph.D.
Expertise/Specialties
virology, hepatology
Research Interests
Research on the molecular mechanism of pathogenesis by viral infection, especially hepatitis viruses and SARS-CoV-2 Clinical studies of viral infectious diseases
Languages
Japanese/English
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Education
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Year Institution Degree 1993 The University of Tokyo M.D. 2002 The University of Tokyo Graduate School of Medicine Ph.D.
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Training
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Years attended Institution Training 1993-06-01 The University of Tokyo Hospital resident 1994-06-01 Tokyo Kosei Nenkin Hospital (currently, JCHO Tokyo Shinjuku Medical Center) resident 1995-06-01 Sanraku Hospital gastroenterology, general practice
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Appointments and positions
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Years Institution Title 2012-12-01 Faculty of Medicine, The University of Tokyo Project assistant professor 2015-04-01 Faculty of Medicine, The University of Tokyo Assitant professor 2017-04-01 Division of Infectious Diseases, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo Associate professor 2022-07-01 Department of Infection Control and Prevention, Graduate School of Medicine and the faculty of medicine, The University of Tokyo Professor
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Board Certifications
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Year Certifications 1997-09-26 Certifified physician of the Japanese society of Internal Medicine 1999-12-06 specialist of the Japanese society of Internal Medicine 2007-03-31 specialist of the Japanese society of Hepatology 2008-01-01 specialist of the Japanese society of Gastroenterology 2022-01-01 Infection Control Doctor
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Selected Publications
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- Moriya K, Fujie H, Shintani Y, Yotsuyanagi H, Tsutsumi T, Ishibashi K, Matsuura Y, Kimura S, Miyamura T, Koike K: The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice. Nat Med. 4: 1065-1067, 1998
- Tsutsumi T, Suzuki T, Shimoike T, Suzuki R, Moriya K, Shintani Y, Fujie H, Matsuura Y, Koike K, Miyamura T: Interaction of hepatitis C virus core protein with retinoid X receptor alpha modulates its transcriptional activity. Hepatology. 35: 937-946, 2002
- Tsutsumi T, Suzuki T, Moriya K, Shintani Y, Fujie H, Miyoshi H, Matsuura Y, Koike K, Miyamura T: Hepatitis C virus core protein activates ERK and p38 MAPK in cooperation with ethanol in transgenic mice. Hepatology. 38: 820-828, 2003
- Tsutsumi T, Matsuda M, Aizaki H, Moriya K, Miyoshi H, Fujie H, Shintani Y, Yotsuyanagi H, Miyamura T, Suzuki T, Koike K: Proteomics analysis of mitochondrial proteins reveals overexpression of a mitochondrial protein chaperon, prohibitin, in cells expressing hepatitis C virus core protein. Hepatology. 50: 378-386, 2009
- Tsutsumi T, Saito M, Nagai H, Yamamoto S, Ikeuchi K, Lim LA, Adachi E, Koga M, Okushin K, Akai H, Kunimatsu A, Yotsuyanagi H: Association of coagulopathy with liver dysfunction in patients with COVID-19. Hepatol Res. 51: 227-232, 2021.
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Academic Societies
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- The Japanese society of Internal Medicine
- The Japanese society of Hepatology
- The Japanese society of Gastroenterology
- The Japanese association for Infectious Diseases
- Japanese Cancer Association
- Japanese society for Infection Prevention and Control
- The Japanese society for AIDS Research
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Honors
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2003 Shering-Plough Award (Encouraging prize) 2006 Research Promotion Award of Daiwa Securities Health Foundation 2007 Research Promotion Award of Daiichi Sankyo Foundation of Life Science 2009 Research Promotion Award of Viral Hepatitis Research Foundation of Japan