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The Department of Gastroenterology specializes in the treatment of disorders of the esophagus, stomach, intestines, liver, gallbladder, pancreas, and other organs of the digestive system.

Medical services

Approximately 90 specialists work together in this department to treat diseases, mainly cancers, of the esophagus, stomach, large intestine, liver, gallbladder, bile duct and pancreas; and other particularly intractable diseases such as hepatitis, pancreatitis and inflammatory bowel disease.

Diagnosis and treatment policy

“Patient-oriented, non-invasive treatment” is our motto. Aiming to achieve maximum outcomes with minimally-invasive approaches, the department adopts a team approach to care for patients with refractory cancer and other intractable diseases. Efforts are focused on treating not only the disease but the patient as a whole.


  • Radiofrequency ablation (RFA) of liver cancer
  • Endoscopic resection of esophageal, stomach, colorectal cancer
  • Stenting plus anticancer chemotherapy for pancreatic and biliary cancer
  • Endoscopic treatment for biliary and pancreatic stones
  • Extracorporeal shock wave lithotripsy for pancreatic stones
  • Treatment of NASH, hepatitis B, C, and H. pylori infection
  • Endoscopic diagnosis and treatment of the small intestine

Target diseases

Hepatitis, steatohepatitis (NASH), cirrhosis, liver cancer, metastatic liver cancer, esophagitis, esophageal cancer, esophageal varix, gastritis, gastric ulcer, gastric cancer, duodenal ulcer, colonic polyp, colon cancer, gallstone, bile duct stone, cholecystitis, gallbladder cancer, pancreatic stone, autoimmune pancreatitis, acute and chronic pancreatitis, bile duct cancer, pancreatic cancer, obstructive jaundice.

Advanced treatments/ Specialized treatments

  • Radiofrequency ablation (RFA) of primary liver cancer and metastatic liver cancer
  • Endoscopic resection of stomach, colon, and esophageal cancer (endoscopic submucosal dissection: ESD)
  • Endoscopic ultrasound (EUS)-guided biliary, pancreatic, and abscess drainage
  • Balloon endoscope-assisted ERCP for surgically altered anatomy
  • Intraperitoneal paclitaxel combined with gemcitabine plus nab-paclitaxel for pancreatic cancer with peritoneal metastasis.
  • Endoscopic examination of the entire small intestine (double balloon small intestinal endoscopy, capsule endoscopy) Endoscopic examination and treatment of the small intestine, which was once referred to as the “Dark Continent
  • Clinical trials for new drugs for liver cancer, pancreatic cancer, colon cancer, biliary tract cancer, and hepatitis B and C

Frequently performed tests and descriptions

  • Abdominal ultrasound examination : gallbladder, pancreas, kidney, spleen, lymph node
  • Upper endoscopy (gastroscopy) : esophagus, stomach, duodenum
  • Lower endoscopy (colonoscope) : colon and rectum
  • Endoscopic ultrasound (EUS) examination for the stomach, duodenum, pancreas, gallbladder, etc.
  • Fibro scan : a new ultrasound scanning technique that measures the stiffness of the liver in place of needle biopsy to check cirrhosis
  • Examinations are performed mainly on an outpatient basis, and patients requiring treatment are hospitalized.
Mitsuhiro Fujishiro

Mitsuhiro Fujishiro


Department of Gastroenterology


M.D. , Ph.D., FJGES


Internal Medicine, Gastroenterology, Gastrointestinal tract diseases, Gastrointestinal endoscopy (diagnosis and treatment)

Research Interests

Pathogenesis in the gastrointestinal diseases, Gastrointestinal endoscopy, Big data science, Artificial intelligence


Japanese / English

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Major diseases and numbers of inpatients treated

Hepatocellular and metastatic hepatic cancer
2 Hepatitis and cirrhosis 117
3 Pancreatic, bile duct, and gallbladder cancer 572
4 Gastric, esophageal, and colon cancer and colon polyps 576
5 Pancreatic stones and chronic pancreatitis 69
6 Choledocholithiasis 285


Areas of expertise, treatment and examination methods

Treatment methods
  1. Radiofrequency ablation for liver cancer
  2. New antiviral therapy for viral hepatitis
  3. Endoscopic submucosal dissection for gastrointestinal cancer
  4. Extracorporeal shock wave lithotripsy
  5. Endoscopic papillary balloon dilatation
  6. Endoscopic placement of bile duct and pancreatic stents
  7. Endoscopic ultrasound-guided biliary drainage
  8. Endoscopic treatment for the severe pancreatitis
  9. Anticancer pharmacotherapy for gastrointestinal cancer
  10. Gastric metal stent

Numbers of major operations and treatments performed

Name of operation/treatment Number
1 Radiofrequency ablation for liver cancer 401
2 Endoscopic Submucosal Dissection for gastirc, colon or esphageal cancer 334
3 Endoscopic Sphincterotomy (EST)
4 Endoscopic papillary balloon dilatation(EPBD, EPLBD) 54
5 Bile duct and pancreatic stent placement 130
6 Extracorporeal shock wave lithotripsy(ESWL) 54
7 Percutaneous Transhepatic Biliary Drainage(PTBD,PTGBD) 75
8 Endoscopic gastrointestinal stenting 51
9 Chemotherapy (Pancreatic, bile duct or gallbladder cancer) 250
10 Chemotherapy (Stomach, colon or esopageal cancer) 56


Major diseases treated in this department and numbers of in- and outpatients

Name of examination Number
1 Abdominal ultrasonography 12,720
2 Upper gastrointestinal endoscopy 11,874
3 Lower gastrointestinal endoscopy 6,383
4 Capsule and balloon endoscopy for small intestine 321
5 ERCP: Endoscopic retrograde cholangio-pancreatography 904
6 Ultrasound-guided hepatic tumor biopsy 131
7 Endoscopic ultrasound 577


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