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Breast and Endocrine Surgery

The Department of Breast and Endocrine Surgery diagnoses and treats mammary gland diseases as well as thyroid and parathyroid diseases. Mammary gland disorders range from malignant tumors including breast cancer, phyllodes tumors, and growing benign tumors. Thyroid and parathyroid diseases include thyroid cancers and tumors, as well as parathyroid adenomas.

Medical services

Specialists and certified physicians affiliated with the Japan Surgical Society and the Japanese Breast Cancer Society, as well as highly experienced specialized physicians affiliated with the Japan Association of Endocrine Surgeons and Japanese Society of Thyroid Surgery carry out diagnosis, surgery, and drug therapy (chemotherapy, molecular targeted therapy and hormone therapy).

Treatment policy

When providing medical services, we place utmost value on each patient’s feelings, thoughts and lifestyle. The most appropriate treatment method is selected by a group of specialists based on a careful review of the results of detailed and precise examinations, and this is thoroughly explained to patients before embarking on the course of treatment.

Specialized areas

Suitable treatment based on close cooperation between Breast and Endocrine Surgery, Radiology, Pathology, Plastic, Reconstructive and Aesthetic Surgery, Nephrology and Endocrinology, and the Department of Clinical Genomics

The best course of treatment is determined by reaching a diagnosis through ultrasound examination, mammography, cytology, needle biopsy, mammotome biopsy, CT and MRI, and by closely coordinating with other departments.

Deciding on a treatment based on abundant experience and explaining

Patients are given information that helps them fully understand the treatment before drug therapies such as anticancer chemotherapy and radiation therapy are carried out.

  • When necessary, the optimum measure to prevent recurrence is considered through multigene assays (such as Oncotype DX).

Target diseases

Breast cancer, mammary gland cancer, phyllodes tumor, fibroadenoma, intraductal papilloma, other mammary gland tumors, hereditary breast and ovarian cancer, thyroid cancer (papillary cancer, follicular thyroid cancer, medullary cancer, undifferentiated cancer), follicular goiter, adenomatoid goiter, Grave’s disease, other thyroid tumors, parathyroid adenoma.

Advanced treatments/ Specialized treatments

Breast cancer treatment

For patients who require breast reconstruction after a total mastectomy, reconstructive mammoplasty and tissue expander insertion surgery are performed in cooperation with Plastic, Reconstructive and Aesthetic Surgery.

Advice on concealing scars with makeup

After surgery, doctors will advise patients about how they can conceal chemotherapy-induced hyperpigmentation with makeup.

  • We place particular emphasis on the treatment of hereditary breast and ovarian cancer syndrome. We coordinate with genomic cancer medicine programs such as the Todai OncoPanel test.
  • A team of Obstetrics and Gynecology specialists will be on hand to discuss whether younger patients want children and wish to opt for fertility-sparing surgery before they commence with breast cancer treatment.

Frequently performed tests and explanations

For breast disorders

Ultrasound examination, elastography, CT, three-dimensional CT, MRI, aspiration biopsy cytology, needle biopsy, mammotome biopsy, sentinel lymph node biopsy (radioisotope, dye, fluorescence), bone scintigraphy, PET scan, testing for inherited BRCA1 and BRCA2 variants.

For Thyroid and parathyroid disorders

Ultrasound examination, CT, MRI, aspiration biopsy cytology, nuclear medicine scan (thallium scintigraphy, MIBI scintigraphy)

Masahiko Tanabe

Masahiko Tanabe


Breast and Endocrine Surgery


M.D. , Ph.D.


surgery on primary breast cancer, systemic treatment on metastatic breast cancer

Research Interests

epigenetic change which is critical for breast cancer development, transcriptional regulation of estrogen receptor alpha (ERα)in breast cancer



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Areas of expertise, treatment and examination methods

  1. Breast cancer
  2. Thyroid cancer
  3. Primary hyperparathyroidism
  4. Basedow's disease
Treatment methods
  1. Breast surgery
  2. Chemotherapy
  3. Hormone therapy
  4. Radiation therapy
Examination methods
  1. Ultrasonography
  2. Mammography
  3. Fine needle aspiration cytology
  4. Core needle biopsy
  5. Vacuum assisted biopsy
  6. Stereotactic mammotome biopsy
  7. MRI
  8. CT
  9. Bonescan

Numbers of major operations and treatments performed

Name of operation/treatment Number
1 Breast-conserving surgery for breast cancer 66
2 Mastectomy for breast cancer 58
3 Mastectomy with tissue expander 10
4 Sentinel lymph node biopsy 94
5 Axillary node dissection 30
6 Resection of benign mammary tumor 14
7 Thyroid cancer resection 41
8 Benign thyroid tumor removal 8
9 Parathyroid adenoma removal 21


Numbers of major and specialized examinations conducted in this department

Name of examination Number
1 Ultrasonograhy 2306
2 Mammography 1539
3 Stereo-guided mammotome biopsy 18


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