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Allergy and Rheumatology

The Department of Allergy and Rheumatology treats rheumatic conditions, including connective tissue disease and allergies such as bronchial asthma. Allergic and rheumatic diseases are similar in that they are caused by abnormalities in the immune system. Our researchers are working to understand the mechanism of abnormal immune system responses with the aim of applying their findings in clinical settings.

Medical services

  • Outpatient clinic: Physicians specializing in rheumatology and allergy are available every weekday. New patients without referral are also accepted.
  • Inpatient ward: The entire staff of the department discusses individual cases (about 30 patients) weekly to determine the most effective therapeutic strategies.

Diagnosis and treatment policy

Many cases of allergic and rheumatic disease are chronic. In determining therapeutic strategy, careful consideration is given to assuring that patients can lead normal lives. Patients with rare diseases may often require individual medical services, diagnosis, therapeutic regimens and care, for which a comprehensive assessment is made based on clinical information and evidencebased medicine (EBM).


The department deals with allergic and rheumatic diseases as well as a variety of disease affecting the respiratory system (excluding pulmonary tumors), kidneys, skin, bones and joints. Since organs throughout the body can often be damaged in patients with these disorders, our aim is not only to treat individual lesions but to take a holistic approach while giving the patient’s desire to perform daily activities special consideration, which is one of the basic principles of internal medicine.

Target diseases

Rheumatic diseases (rheumatoid arthritis, systemic lupus erythematosus, connective tissue disease, including vasculitis syndrome, and other disorders similar to connective tissue disease), allergic diseases (bronchial asthma, eosinophilic disorder, drug-induced allergy, etc.) and periodic fever syndrome.

Frequently performed tests

Broncoscopy for visual examination of the lung and renal biopsy to evaluate lupus nephritis and ultrasonography for assessment of synovitis are performed.

Keishi Fujio

Keishi Fujio


Allergy and Rheumatology


M.D. , Ph.D.


Rheumatology, Internal Medicine

Research Interests

Clinical Immunology, Basic Immunology


Japanese, English

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Areas of expertise, treatment and examination methods

  1. Collagen diseases, such as rheumatoid arthritis and systemic lupus erythematosus
  2. Allergic diseases, such as bronchial asthma and eosinophilic pneumonia
Treatment methods
  1. Treatment of rheumatoid arthritis using biologicals
  2. Treatment of disorders related to collagen disease (Behcet's disease and ankylosing spondylitis) using biologicals
  3. Treatment of bronchial asthma using biologicals

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