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Advanced Medical Center for Heart Failure
The Advanced Medical Center for Heart Failure strives to provide the
highest level of medical care in Japan for heart failure patients. It is also
responsible for training heart failure specialists and other specialized
staff.
Medical services
The center collaborates with a wide range of university hospitals and core regional medical institutions to accept patients who require heart transplants or Ventricular Assist Device (VAD) implantation. In addition to cardiovascular medicine and cardiovascular surgery, the center provides medical care with a heart team consisting of recipient transplant coordinators, pharmacists, clinical engineers, and physical therapists. In addition to such medical cooperation efforts, the center is also responsible for training heart failure specialists and other specialized staff by accepting trainees.
Specialties
- Heart transplantation: Performed 247 heart transplants to date (as of 30 April 2025), the largest number in Japan.
- Ventricular Assist Device (VAD): The center can employ all types of VADs approved in Japan, making it possible to choose the most suitable model according to each patient’s physique and heart failure condition. It is also recognized as a facility that can perform destination therapy.
- Drug therapy for heart failure: The center has extensive experience in the use of heart failure drugs, including those that have been approved in recent years.
- Introduction of disease modifying drugs for cardiac amyloidosis: The center has been certified to introduce disease modifying drugs by The Japanese Circulation Society and have already gained a significant amount of experience with the drug.
Special medical treatment
The center participates in a Phase I/II clinical trial of allogeneic iPS cell-derived cardiospheres for severe heart failure due to ischemic heart disease, and a clinical trial of human iPS cell-derived cardiovascular cell multilayers for dilated cardiomyopathy.
Target diseases
Target diseases include idiopathic cardiomyopathies such as dilated cardiomyopathy and hypertrophic cardiomyopathy, various types of secondary cardiomyopathy, and all cases of heart failure regardless of underlying disease.
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