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Advanced Medical Center for Heart Failure

The Advanced Medical Center for Heart Failure strives to provide the highest level of medical care in Japan for heart failure patients. It is also responsible for training heart failure specialists and other specialized staff.

Medical services

The center collaborates with a wide range of university hospitals and core regional medical institutions to accept patients who require heart transplants or Ventricular Assist Device (VAD) implantation. In addition to cardiovascular medicine and cardiovascular surgery, the center provides medical care with a heart team consisting of recipient transplant coordinators, pharmacists, clinical engineers, and physical therapists. In addition to such medical cooperation efforts, the center is also responsible for training heart failure specialists and other specialized staff by accepting trainees.


  • Heart transplantation: Performed 200 heart transplants to date (as of 30 April 2023), the largest number in Japan.
  • Ventricular Assist Device (VAD): The center can employ all types of VADs approved in Japan, making it possible to choose the most suitable model according to each patient’s physique and heart failure condition. It is also recognized as a facility that can perform destination therapy.
  • Drug therapy for heart failure: The center has extensive experience in the use of heart failure drugs, including those that have been approved in recent years.
  • Introduction of Vyndaqel for cardiac amyloidosis: The center has been certified to prescribe Vyndaqel by The Japanese Circulation Society and have already gained a significant amount of experience with the drug.

Special medical treatment

The center participates in a post-marketing clinical trial of HeartSheet, a skeletal myoblast sheet to be transplanted onto the surface of the heart.

Target diseases

Target diseases include idiopathic cardiomyopathies such as dilated cardiomyopathy and hypertrophic cardiomyopathy, various types of secondary cardiomyopathy, and all cases of heart failure regardless of underlying disease.

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