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Tissue Bank

The Tissue Bank plays a critical role in the preservation and distribution of allogeneic heart valves, blood vessels, and bone tissues donated by deceased donors. These tissues are cryopreserved and allocated to medical institutions throughout Japan to support patients requiring transplantation. Similar to organ transplantation, tissue transplantation is fundamentally grounded in the voluntary consent of donors and their families. The Tissue Bank is also actively engaged in public awareness and educational initiatives aimed at advancing the field of transplant medicine.

Institutional Profile

This Tissue Bank holds Category I accreditation from the Japanese Society for Transplantation, which authorizes the provision of multiple types of allogeneic tissues to external medical facilities. As one of the few institutions in Japan with such capabilities, the bank employs certified transplant coordinators who work in close collaboration with clinicians from relevant departments to oversee the entire process from tissue procurement to clinical supply.

Clinical Indicators

  • Heart Valve Transplantation
    Indications include: Infective endocarditis, Prosthetic valve endocarditis, Aortic root abscess, Hypoplastic left heart syndrome, Reconstructive surgery of the pulmonary artery or aorta
  • Vascular Transplantation
    Arterial grafting: Prosthetic graft infections, mycotic aneurysms Venous grafting: Hepatobiliary-pancreatic disorders, congenital cardiovascular anomalies
  • Bone Transplantation
    Hip joint disorders, Spinal pathologies, Knee and ankle joint diseases, Bone neoplasms, Segmental bone defects

Program Characteristics

[Heart Valve and Vascular Tissue Transplantation]
  • Allogeneic heart valve and vascular grafts exhibit superior resistance to infection compared to synthetic prostheses. Furthermore, these tissues do not necessitate long-term anticoagulant therapy, offering distinct advantages for populations such as athletes and women planning pregnancy.
  • Operational Framework: The bank works in collaborates with the Japan Organ Transplant Network and other tissue banks. Surgical teams comprising cardiovascular and hepatobiliary-pancreatic/transplant surgeons are deployed to donor cases, primarily within the Kanto region.
  • Clinical Activity (1998 -2024): Total donor cases: 264 Total recipient cases: 1,125 across 44 recipient institutions
  • [Bone Tissue Transplantation]
  • Allogeneic bone graf ting is an established standard therapy employed worldwide for the reconstruction of skeletal defects. Transplanted bone provides durable mechanical strength and gradually undergoes biological remodeling, being resorbed and replaced by autologous tissue over time.
  • Operational Framework: In collaboration with the Department of Orthopedic Surgery, femoral bone segments resected during total hip arthroplasty for osteoarthritis are harvested as graft material. These tissues are subjected to rigorous processing and stored under cryogenic conditions.
  • Clinical Activity (2018 -2024): Total donor cases:54 Total recipent cases:31
Sumihito TAMURA

Sumihito Tamura

Departments/Divisions

International Medical Center, Tissue Bank, Artificial Organ and Transplantation Surgery

Titles

M.D., Ph.D., F.A.C.S.

Expertise/Specialties

Surgery, Heaptology, Liver Transplantation, Tissue Transplantation, Medical Education

Research Interests

Liver Disease, Liver Trasnplantation, Organ Transplantation, Donor Safety in Living Liver Donor, Tissue Transplantation, Tissue Banking, Cyropreservation of homograft, Medical Education, Surgical Training, Medical Care for Foreign Patients in Japan, Multicultural Resource for Health Care, Cross border clinical medicine

Languages

Japanese / English

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