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Organ Transplantation Center

With the increase in the number of brain-dead donor transplantations (liver, heart, lung, and kidney), living donor (liver, lung, and kidney) and donated kidney transplantations, and implantable ventricular assist device operations, the Organ Transplantation Service was reorganized and newly established in 2020 as the Organ Transplantation Center.

Medical services

Each organ transplant division and coordinators at the Center cooperate with related departments to ensure smooth operations. The Center provides support to solve the problems faced by living donors and recipients and their families.

Diagnosis and treatment policy

Transplant indications are determined by the Transplantation Indication Review Committee for each organ, and each case is examined in detail within each division.


[Liver transplantation] (as of May 2023)
  • Living donor partial liver transplantation : 815 cases have been performed to date. 1, 5 and 10-year survival rates are exceptionally good at, respectively, 93%, 85%, 83%. Safety is the first priority for the May living donor and a rigorous preoperative examination is performed.
  • Brain-dead donor liver transplantation : 79 brain-dead donor liver transplants (including 4 simultaneous liver and kidney transplants) have been performed, with a 5-year survival rate of 96%.
  • The Center also has experience with auxiliary partial orthotopic liver transplants and domino liver transplants.
[Heart transplantation] (as of May 2023)
  • Brain-dead donor heart transplantation : 200 heart transplants (15 pediatric transplants) have been per formed (the highest number in Japan), with outstanding results as exemplified by the 10-year survival rates of 88% respectively. The Center has the largest heart transplant waiting list in Japan with 241 patients currently registered.
  • Implantable ventricular assist device : 235 operations for 275 patients have been carried out to implant a ventricular assist device as a circulatory support for severe heart failure (second in the country). 1, 5-year survival rates are exceptionally good at 94% and 87% respectively. Currently, around 64 patients are attending the Center.
[Lung transplantation] (as of May 2023)

Lung transplantation began in April 2015 and to date, 26 living donor lung transplants and 125 brain-dead donor lung transplants have been performed. The number of transplants has increased in recent years, with 32 lung transplants performed in 2021 (the highest number in the country). The Center may accept difficult cases too, including lung transplants in patients who are depended on mechanical ventilators and/or artificial lungs (ECMO).

[Kidney transplantation] (as of May 2023)

The Urology and Nephrology divisions cooperate to provide medical care, making use of their respective areas of expertise from the preoperative stages to postoperative management.

  • Kidney transplants between blood relatives or non-blood relatives (e.g. married couples). Blood group incompatible kidney transplants and pre-dialysis preemptive kidney transplants are also performed. The Center strives to reduce the burden on the donor through endoscopic procedures. It has performed 79 cases to date, with a 5-year survival rate and take rate of 100%.
  • Donated kidney transplantation : There are currently 81 patients on the Center’s waiting list. To date, 21 donated kidney transplants have been performed.
Minoru Ono

Minoru Ono


Department of Cardiovascular Surgery & Department of Cooperative Unit of Medicine and Engineering Research


M.D. , Ph.D.


Adult Cardiac Surgery, Minimally Invasive Cardiac Surgery, Robotic Cardiac Surgery, Mitral Valve Plasty, Off-pump Coronary Artgery Bypass Surgery, Ventricular Assist Device, Heart Transplantation

Research Interests

Surgical Treatment of End-stage Heart Failure (Ventricular assist device, Heart transplantation, Mitral complex plasty), Device Development for Minimally Invasive Surgery, Regenerative Medicine



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