Top > Find a Doctor > Makoto Aihara

Makoto Aihara

Makoto Aihara



M.D., Ph.D


Glaucoma, Neurobiochemistry, Ocular Pharmacology

Research Interests

・the analysis of the risk factor activating glaucoma
・the study of the surgical outcomes of glaucoma
・the elucidation to the pathology of increasing intraocular pressure through bioactive lipids
・the development of new drops for glaucoma


Japanese, English

Year Institution Degree
1989 Faculty of Medicine, University of Tokyo M.D.
1998 Dept. of Biochemistry and Molecular Biology, University of Tokyo Ph.D
Years attended Institution Training
1989-1990 University of Tokyo Hospital, Tokyo, JAPAN Fellow
Appointments and positions
Year Institution Title
Dept. of Ophthalmology, University of Tokyo Hospital Assistant
1998-2000 ・Dept. of Ophthalmology,  University of Tokyo Hospital
・Kanagawa Academy of Science and Technology
・Assistant Professor
・Visiting researcher
2000-2003 Hamilton Glaucoma Center, University of California, San Diego Research fellow/Assistant research scientist
2003-2012 Department of Ophthalmology, University of Tokyo Hospital Instructor/Associate professor
2012-2015 ・Yotsuya-Shirato Eye Clinic
・Dept. of Ophthalmology, Tokyo Medical and Dental University Medical Hospital
・Vice director
・Specially-appointed professor
2015 Dept. of Ophthalmology,  University of Tokyo Professor and Chair
Board Certifications
Year Certifications
1989 Japanese medical board
2000 California medical board (temporary)
Selected Publications
  • Honjo M, Igarashi N, Nishida J, Kurano M, Yatomi Y, Igarashi K, Kano K, Aoki J, Aihara M. Role of the Autotaxin-LPA Pathway in Dexamethasone-Induced Fibrotic Responses and Extracellular Matrix Production in Human Trabecular Meshwork Cells. Invest Ophthalmol Vis Sci. 2018 Jan 1;59(1):21-30.
  • Uchida T, Honjo M, Yamagishi R, Aihara M. The Anti-Inflammatory Effect of Ripasudil (K-115), a Rho Kinase (ROCK) Inhibitor, on Endotoxin-Induced Uveitis in Rats. Invest Ophthalmol Vis Sci. 2017 Oct 1;58(12):5584-5593.
  • Honjo M, Igarashi N, Kurano M, Yatomi Y, Igarashi K, Kano K, Aoki J, Weinreb RN, Aihara M. Autotaxin-Lysophosphatidic Acid Pathway in Intraocular Pressure Regulation and Glaucoma Subtypes. Invest Ophthalmol Vis Sci. 2018 1;59(2):693-701
  • Ohtani S, Shimizu K, Nejima R, Kagaya F, Aihara M, Iwasaki T, Shoji N, Miyata K. Conjunctival Bacteria Flora of Glaucoma Patients During Long-Term Administration of Prostaglandin Analog Drops. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3991-3996.
Academic Societies
  • Japanese Ophthalmological Society
  • Japanese Glaucoma Society
  • Japanese neuroophthalmological society
  • Japanese ocular phamacological society
  • World Glaucoma Association
Editorial Boards
  • Japanese Journal of Ophthalmology
  • Journal of Glaucoma
  • Journal of ocular pharmacology and therapeutics

page top